The pro-survival protein Bcl-xL is critical for the resistance of tumour cells to DNA damage. We have previously demonstrated, using a mouse cancer model, ...

  journals.plos.org

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Apoptotic responses can be observed in wild type cells responding to AIM2 or NLRP3 stimuli [58]. ... In contrast, BCL-2 can negatively regulate NLRP3 inflammasome ...

  www.ncbi.nlm.nih.gov

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... BCL-2 inhibitor venetoclax. Preclinical data demonstrated the anti-leukemic efficacy of venetoclax in AML and its synergy when combined with hypomethylating ...

  pubmed.ncbi.nlm.nih.gov

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Illumina bcl2fastq2 Conversion Software was used to demultiplex samples into individual samples and to convert per-cycle BCL base call files into FASTQ files ...

  www.ncbi.nlm.nih.gov

bcl-2-Associated X Protein / genetics; bcl-2-Associated X Protein / physiology*. Substances. Amino Acid Chloromethyl Ketones; Antineoplastic Agents, Phytogenic ...

  pubmed.ncbi.nlm.nih.gov

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